Federico Prokopczuk et al. engineered a superinfective phage (eSI-Pf) based on the Pf4 phage, which is able to infect Pseudomonas aeruginosa. They tested it as a phage therapy tool for the treatment of life-threatening burn wound infections and found that while it was not able to maintain a sustained reduction in bacterial burden, it did prevent dissemination of P. aeruginosa from the burn site.