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Instill Science / post-yk3f5xde
April 20, 2023jessica-sacher
Engineered phage Research paper

Federico Prokopczuk et al. engineered a superinfective phage (eSI-Pf) based on the Pf4 phage, which is able to infect Pseudomonas aeruginosa. They tested it as a phage therapy tool for the treatment of life-threatening burn wound infections and found that while it was not able to maintain a sustained reduction in bacterial burden, it did prevent dissemination of P. aeruginosa from the burn site.

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