In a new preprint, Enea Maffei (University of Basel) and colleagues describe a new phage, Paride, which is able to kill dormant, antibiotic-tolerant bacteria. They suggest that this phage hijacks weak spots in the dormant physiology of antibiotic-tolerant bacteria that could be exploited as Achilles’ heels for the development of new treatments targeting resilient bacterial infections.
In a new preprint, Enea Maffei (University of Basel) and colleagues describe a new phage, Paride, which is able to kill dormant, antibiotic-tolerant bacteria. They suggest that this phage hijacks weak spots in the dormant physiology of antibiotic-tolerant bacteria that could be exploited as Achilles’ heels for the development of new treatments targeting resilient bacterial infections.