June 9, 2023 ∙ jessica-sacher
Phage resistance
Review
Phage therapy
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Agnès Oromí-Bosch and colleagues published a new report on phage resistance-related challenges associated with phage therapy. They review two main strategies for mitigating resistance in phage therapy: 1) smartly identify/design the phages that are administered; 2) use phages that drive evolutionary trade-offs (in bacteria) that are biomedically desirable. Twitter thread by coauthor Jyot Antani here