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Instill Science / post-jR9TwDnQ
February 15, 2023jessica-sacher
Research paper Structural Biology

In a new paper in Cell, Brianna Duncan-Lowey (Harvard Medical School) and colleagues determined the cryo-EM structures of the RADAR defense complex, revealing RdrA as a heptameric, two-layered AAA+ ATPase and RdrB as a dodecameric, hollow complex with twelve surface-exposed deaminase active sites.

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