May 25, 2023 ∙ jessica-sacher
Research paper
Lysogeny
Phage therapy
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Phage utility against Burkholderia cepacia complex species has been restricted by the prevailing paradigm of only using rare, obligately lytic phages, due to the perception that lysogenic phages are therapeutically unsuitable. Philip Lauman and Jonathan Dennis here show that many lysogenization-capable phages exhibit powerful in vitro antibacterial activity both alone and through synergy with other phages.