Instill Science

A place to discuss science, share work, and find mentors and collaborators

Instill Science / post-SKBgCYwK
April 20, 2023jessica-sacher
CRISPR Phage defense Research paper

Michael Schelling et al. published a new paper in PLOS Biology on how CRISPR-Cas effector specificity and cleavage site determine phage escape outcomes. They find that most pre-existing crRNA mismatches lead to phage escape, regardless of whether the mismatches ablate Cas12a cleavage in vitro.

Loading ...
No comments yet. Be the first to comment!